Tuesday, December 24, 2019

Alzheimer s Disease A Progressive Disease - 1667 Words

Alzheimer’s Disease is a progressive disease that destroys memory and other important mental functions. Brain cells in Alzheimer’s disease dies and degenerate causing the loss of memory and mental functions. Alzheimer’s is the sixth leading cause of death in the U.S.A. Alzheimer’s Disease is named after Dr. Abis Alzheimer. In 1906, Dr. Alzheimer noticed changes in the brain tissue of a lady who had died of an unusual mental illness that was very unknown. The woman s’ symptoms included memory loss, language problems, and unpredictable behavior that people with Alzheimer’s have almost often of times. Alzheimer’s disease is the most common form of dementia in this world and it’s thought to be the most progressive disease of all diseases. Also this disease gets progressively worse over time. The majority of people with Alzheimer’s are sixty-five years old or older, however, almost five percent of the people have earl y-onset Alzheimer’s. Early-Onset Alzheimer s is known as Alzheimer s at a younger age which appears at the ages of forties and fifties. In early stage Alzheimer’s, memory lost is very mild. With late Alzheimer’s, individuals lose the ability to carry on conversations and respond to their environment. People with Alzheimer’s often live an average of eight years after their symptoms become noticeable to others. There are major symptoms to Alzheimer’s disease, however, main symptoms that you may notice is memory loss and confusion. Overtime, theShow MoreRelatedAlzheimer s Disease : A Progressive Disease925 Words   |  4 PagesAlzheimer s disease is a progressive disease that destroys memory and other vital mental functions. Alzheimer s disease is the most common cause of dementia, a group of brain disorders that cause the loss of intellectual and social skills. AD can eventually render a person unable to function in society and to even care for themselves. Since the disease is the 6th leading cause of death in the United States constant research is being done to try to prevent it and to find a cure. Alzheimer s diseaseRead MoreAlzheimer s Disease : A Progressive Disease1663 Words   |  7 Pages Alzheimer s disease is a progressive disease that destroys memory and other important mental functions. At first, someone with Alzheimer s disease may notice mild confusion and difficulty remembering. Eventually, people with the disease may even forget important people in their lives and undergo dramatic personality changes. Alzheimer s disease is the most common cause of dementia — a group of brain disorders that cause the loss of intellectual and social skills. In Alzheimer s disease, theRead MoreAlzheimer s A Progressive Disease865 Words   |  4 Pagesin their place: gradually losing your freedom, your memory, and your very own identity. Alzheimer’s is a progressive disease that slowly destroys the brain’s function of memory and cognition. Eventually, it terminates the person’s ability to do everyday tasks and requires the person to be under around-the-clock care. Alzheimer’s disease is named after Dr. Alois Alzheimer. In 1906, Dr. Alzheimer noticed changes in the brain tissue of a woman who had died of an unknown mental illness (â€Å"Alzheimer’sRead MoreAlzheimer s Disease : A Serious Progressive Disease1058 Words   |  5 PagesAlzheimer’s disease is a serious progressive disease. There is no cure for it. There have been an estimated 5.3 million people that had this disease in 2015. 5.1 million of those people were 65 years old or older. 200,000 of those people where under 65 and had the detection of the early stages of Alzheimer’s. Alzheimer’s Association (2015) Early detection of this disease is important and imperative in the treatment. Many patients that are suffering from Alzheimer’s Disease don’t find out from theirRead MoreAlzheimer s Disease : A Progressive Neurodegenerative Disease2372 Words   |  10 Pagesdementia is brought forward. Alzheimer’s Disease (AD) is a brain d isease, is the most common type of dementia, and affects majority of people 60 years or older (1,14). It is a progressive neurodegenerative disease, which only continues to worsen over time. Each individual is affected differently with symptoms and the progression. As of right now there is no cure for it (14). Biology of Alzheimer’s Disease Alzheimer’s is a progressive neurodegenerative disease, which attacks the brain. It is not knownRead MoreAlzheimer s Disease : A Progressive Degenerative Disease2632 Words   |  11 PagesIntroduction Alzheimer s disease (AD) is a progressive degenerative disease of the brain from which there is no recovery. There are three brain abnormalities that are the hallmarks of the Alzheimer’s disease is initially caused by plaques buildup in the brain’s neurons as illustrated in figure 1. The support structure that allows the flow of the nutrients through the neurons gets damaged and ultimately there is loss of connection among the neurons and they die off (National Institute of Health,Read MoreAlzheimer s Disease : A Progressive Degenerative Disease Of The Brain981 Words   |  4 PagesAlzheimer’s disease is a type of dementia that gradually destroys brain cells, affecting a person’s memory and their ability to learn, make judgments, communicate and carry out basic daily activities. The disease is a progressive degenerative disease of the brain. It was first described by the German neuropathologist Alois Alzheimer in 1905 (Selkoe, 2016). The average life expe ctancy of an Alzheimers patient is between five and ten years, but some patients today have live for up to 15 years afterRead MoreAlzheimer s Disease : A Progressive Decline1240 Words   |  5 PagesAlzheimer’s disease is a progressive decline in cognitive function. It affects the brain by damaging brain cells resulting in a decreased in cognitive function, physical mobility, swallowing and fine motor skills. This disease approximately 5.1 million Americans aged sixty-five or older (Alzheimer s Association, 2015) of which approximately 700,000 will likely die this year (Alzheimer s Association, 2015) of related symptoms such as aspiration pneumonia due to decreased swallowing ability. TheRead MoreAlzheimer s Is A Progressive Disease973 Words   |  4 Pagesaffected as well as those who may be caring for them and their families. This change is that of the disease Alzheimer’s. Alzheimer’s is a progressive disease that destroys memory and other important menta l functions. This disease affects more than 5 million Americans and continues to increase. With this disease on the increase, it begs the question if there is a way to prevent this debilitating disease or at least some kind of early diagnosis. Though there is no concrete way to determine the etiologyRead MoreAlzheimer s Is A Progressive Disease1630 Words   |  7 Pagesfor her but also for everyone around us. Alzheimer’s doesn’t affect only the person living with the disease but also those who care for them and love them; this is how my family is also a victim of Alzheimer’s. Alzheimer’s is a progressive disease that affects memory, thinking and behavior; making it the 6th leading cause of death in the United States. There are no treatment methods to stop the disease from progressing; therefore there is no cure. What causes most pain in families is seeing how the

Monday, December 16, 2019

Cost and Price Analysis Free Essays

Cost and Price Analysis Instructor:Name: Class:Finance 230Date: Period:Results: 1)Why is it important for the government to exercise good fiscal judgment when spending funds? Government employees are held responsible for use of good judgment so those excessive prices are not paid. 2)List and describe four types of market based pricing. Be sure to provide at least one (1) example of each type. We will write a custom essay sample on Cost and Price Analysis or any similar topic only for you Order Now Competitive Offers – response to solicitation encouraging competing offers Established Catalog Price – Published by the seller in a regularly maintained catalog or price list Established Market Price – substantiated from sources independent of the seller: and are current sales prices established in the normal course of trade between buyers and sellers free to bargain in the market place. Established by Law or Regulation – customers are consistently impacted by the established prices. )List 3 reasons that government buyers have significant advantages in getting fair and reasonable prices. The government is the only buyer – which has a strong negotiating position on pricing. High volume purchase – suppliers like to deal with high volume buyers and are inclined to give better prices to such buyers. Anit-Deficiency Act – requires the government agencies have the money to pay for the contract work before signing the contract. 4)Compare and contrast cost, price and profit. Price refers to the amount of money that consumers have to give up to acquire goods or service. Profit is what ever monetary amount is left after all cost has been paid. 5)List and explain the two acceptable procedures for obtaining competitive prices. Sealed Bidding – A process by which government needs are made known by a solicitation called and Invitation for Bids (IFB). Negotiation is the contracting method that ma be used when sealed bidding is inappropriate. Competitive Proposals A process by which government needs are made known by a solicitation called a Request for Quotation (RFQ) 6)Compare and contrast cost and financial accounting. List two (2) examples each of conditions that warrant the use of cost and financial accounting procedures. Cost accounting – is a procedure which enables firms to keep track of the costs that apply to each individual contract or major task they under take. Ex cost acct. – estimate the cost of work before actually undertaking it. Financial accounting – is the accumulation of information that enables the firm to know how much total cost and profit they made in a particular period of time. Ex. 7)What are the three major classifications of costs? Reasonable, allowable, and allocable cost Variable fixed, and semi-variable cost Direct and indirect cost 8)Compare direct and indirect costs. Direct cost – direct labor, direct materials, and some other costs specifically associated with particular contracts are classified as direct costs. Indirect cost – are any cost that are not direct. Cost that apply across the board to large parts not conveniently chargeable to one particular contract. How does the government contracting officer ensure the costs are reasonable, allowable and allocable? Reasonable Cost – in its nature and amount, it does not exceed that which would be incurred by a prudent person in the conduct of a competitive business. Allowable Cost – allowability of a particular cost under cost principles must be determine using FAR Part 3. Each principle is based on laws and policies. The decision for determing allowable of a particular cost rest with the Contracting Officer. Allocable Costs – alloacable if I is assignable or chargeable to one or more cost objectives on the basis of relative benefits received or other equitable relationship. )When may certified cost or pricing data be required? The head of an agency shall require offerors, contractors, and subcontractors to make cost or pricing data available as follows: An offeror for a prime contract entered into using procedures other than sealed-bid procedures shall be required to submit cost or pricing data before the award of a contract if— in the case of a prime contract, the price of the contract to the is expected to exceed $500,000; and in the case of a prime contract entered into on or before, the price of the contract to the United States is expected to exceed $100,000. n the case of a change or modification made to a prime contract referred to in subparagraph the price adjustment is expected to exceed $500,000; in the case of a change or modification, to a prime contract that was entered , the price adjustment is expected to exceed $500,000; and in the case of a change or modification not covered by clause (i) or (ii), the price adjustment is expected to exceed $100,000. 10)If the government were to determine that significant overpricing occurred because of defective cost or pricing data, what options may the contracting officer explore prior to award? What may the contracting officer consider after award? The Truth in Negoatation Act – an examination of defective pricing in government contracting 11)Explain the level of importance associated with the detailed analysis of direct labor costs when determining a fixed-price contract. Price analysis shall be used when cost or pricing data are not required in determining the reasonableness of the prime contract price. Some firm-fixed-price contracts may entail substantially less cost risk than that of direct costs, such as material and labor, and associated indirect costs. 2)When determining proposed hourly wage rates, list three (3) options an offeror explore. Plantwide rate, Departmental Rate, and Rates by Labor Category 13)List, in comparison, what process improvements benefits realized from the learning curve and improvement curve. What are the expectations of each curve? Theroy called learning curve because it is belived thath learning workers caused most of the time saving, Studies showed that other factors, such as equipment and set-up improvements, also help reduce unit production time. It is called various names improvement curve, experience curve and time reduction curve. 14)How does a company effectively manage the overhead expense? What are the typical expenses included in overhead? Overhead expenses are those production and nonproduction costs not readily traceable to specific jobs or processes. Overhead expenses encompass three general areas: indirect materials, indirect labor, and all other miscellaneous production expenses, such as taxes, insurance, depreciation, supplies, utilities, and repairs. Therefore, overhead expense is part of the total costs of maintaining and staffing a business. 15)Categorize the following expenses as either Overhead or General Administrative: a. Lease b. Entertainment Expense c. Travel Expense d. Payroll Expense e. Marketing Expense f. Mileage g. Professional Development h. Utilities i. Communications Expense j. Goodwill k. Research and Development Costs l. Taxes m. Patent Costs n. Bad Debts o. Lobbying and other Political Costs 16)The scrap allowance includes spoilage and shrinkage. List two (2) similarities and differences between the three categories. Scrape allowance is extra amount of material or parts required to be sure that enough material will be avaible to make the final product. Scrap is unadvoidable. Spoilage is a different from scrape because it is the direct result of someone making a mistake or a machine getting out of adjustment or a similar problem. Shrinkage is another factor. This can be the result of nature. 17)Explain the following concepts: a. Underabsorption under absorption is when the actual budgeted overhead is less than the planned overhead b. Overabsorption Occurrence of credit balance in factory-overhead account, resulting from excess of overhead applied to work-in-process inventory over the amount of overhead actually incurred. c. Exact Absorption The chances of absorbing the exact actual amount of overhead by a series of many customer billings throughout the year are nil. 18)Describe the following methods in conducting price analysis: a. Comparison of proposed prices received in response to the solicitation These methods consist of comparing offered prices to each other to decide which are reasonable b. Comparison of prior proposed prices and contract prices with current proposed prices Method most frequently used for government price analysis when agency has had a history of contracting for the same products or services. c. Comparison with competitive published price lists Catalogs are recognized as fairly reliable guides on current prices being paid by consumers in general. Established catalog or market price. The price paid for commercial items prices for items sold in substantial. Established catalog price, Established market price, and Price paid for Commercial items. . Visual Analysis FAR 5. 404-1(b) (4) says value analysis can give insight into the relative worth of a product, and government may use it in conjunction with other price analysis techniques. 20)Facilities cost of capital is allowable if the contractor’s have which of the following: (a) Capital investment is measured, allocated to contracts and cost as required by CAS 414 (b) Contractor has adequate records to show compliance with CAS 414 (c) Estimated facilities capital cost of money is specifically proposed for the contract under which it is claimed (d) All of the above 1) Compare and contrast Distributed Facilities and Undistributed Facilities. Distributed facilities are those that are clearly and directly assigned to specific overhead or G accounts. Undistribute Facilities are facilities capital costs incurred for more than one indirect cost pool. The cost of these facilities must be allocated to the indirect cost pools that bebefit from them. 22) Facilities capital cost of money is an a. Allocatable cost b. Allowable cost c. Variable cost d. Imputed cost e. Both b and d 23). What does the acronym CASB mean in Facilities Capital Cost of Money a, Capital Accounting System Branch b. Cost Accounting Standards Board c. Cost Analysis Standards Board d. Both a b 24) Which form is used to calculate the capital cost of money: a. Form CASB-CMF b. DD 1861 c. SF 182 d. All of the above. 25) In which (1) one of the three ways can a contract auditor assist the contracting officer in contract pricing? Reviewing and evaluating proposed or incurred costs 26) Contracting Officers will often ascertain that the contractor’s accounting system meets this requirement by commissioning a ______________________? Pre-award Survey of Prospective Contractor Accounting System ( PSPCAS) 27) Contract auditor is called on by a contracting officer to determine if the prospective contract meets what? Responsible financial capability standard of FAR 9. 104-1 28) What unsupported costs are proposed or incurred costs on which the auditor is unable to render an opinion? Regarding reasonable, allowability, or allocability. 29) What does the acronym DCAA mean? Defense contract Audit Agency 30) What is the total Cost Approach? How is it used? It shows all cost incurred in the original contract estimate and were the attributes to the contract were changed. It shows the government at fault and recognizes that neither the contractor nor any third party is at fault. 31) List the two principles that prevail in measuring equitable adjustment. Some cost impact must result from the contract change The contract and government are to remain whole. 32) Why is there a format for submitting proposals for equitable adjustments and when is it used. This formal procedures is a methodical way o document the calculation of the equitable adjustment. When contractors submit certified cost or pricing data if the expected value of the contract modification exceeds $650,00. 00. 33) What is the name of the formula that is widely used when computing unabsorbed overhead resulting from government caused delays? Eichleay Formula 34) How can contractors segregate the cost of performing changed work? They usually assign specials accounting codes to the transactions attributed to the changed work. 35) What is the main misconception about profit and fee? Negotiated profit or fee is what the contractor will actually get. 6) What three major requirements must government contracting officers adhere to according to the Contracting Officer Responsibilities (FAR 15. 404-4)? Profit fee Pre-negotiation objective, Facilities Capital Cost of Money, Statutory Limitations of Prices or Fees 37) Name six major factors bearing on profit levels for government contracts. Contractor Effort, Contract cost rack, Federal Socioeconomic programs, Capital Investmen ts, Cost Control and other Past Accomplishments, Independent Development. 38) What is the general approach used by all the structured profit systems. The structured profit systems establish a total profit objective by adding profit increments for various major cost inputs and for other contract factors. 39) What are the major categories listed under the approach of Profit Determination – Overhead? High skill supervision, clerical and support, depreciation or rent (complex) depreciation or rent (routine), fringe benefits administrative, routine expense, and total overhead costs. 40) List three important factors that every business must consider before doing business with the government. How to cite Cost and Price Analysis, Papers

Sunday, December 8, 2019

Evelines Conflict free essay sample

A study of the conflicts faced by Eveline, the main character in James Joyces `Dubliners`. An essay which examines the internal conflict that paralyzes the female protagonist, Eveline, in the novel `Dubliners` by James Joyce, as she stands upon the event horizon of a new life, and a new set of possibilities. It shows that at this particular moment in her life, Eveline finds herself at a crossroads, considering whether or not she should leave her home and her abusive, alcoholic father in order to travel to a far away and exotic land to begin a new life, full of promise and hope. `In the end, these dramatic feelings and impulses were not suggestive of Eveline`;s resolve to change her life, but instead, they were evidence of her desperate inward struggle to convince herself that she could be someone else. She was fighting for her life at that very moment, more passionately than she had ever fought before. We will write a custom essay sample on Evelines Conflict or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page But, as we have seen, she was struggling against the oppressive weight of her memories, her social responsibility, and her own self definition, all of which would work against her and work to sabotage any attempt she might make to seek happiness, a new life, and ultimately salvation.